About: Molecular dynamics of topoisomerase-II with PSAH 5c. (a) RMSD diagram of topoisomerase-II

4G0U

Design and Synthesis of Novel Podophyllotoxins Hybrids and the Effects of Different Functional Groups on Cytotoxicity

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Details.

Scientist
Lianxiang luo
Protein
topoisomerase-II
Ligand
PSAH
Simulation Duration
100ns
InChIKey
N/A
SMILES
N/A
Molecular Formula
N/A
Protein Details
catalyzes a transient breakage and reunion of double-stranded DNA.
Ligand Details
PSAH can be attributed to the substitution of chlorine on the benzene and the modifi cation of the coumarin core. The combination effect of topoisomerase-II and 5c is tight.
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