About: Apo enzyme (Black), Glm complex (red), Mlm Complex (Blue)

7BZM

Structural Basis of Specific Glucoimidazole and Mannoimidazole Binding by Os3BGlu7

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Information

Details.

Scientist
Thanyada Rungrotmongkol
Protein
glucoimidazole (GIm) and mannoimidazole (MIm)
Ligand
Os3BGlu7β-glucosidase
Simulation Duration
1000 ns
InChIKey
N/A
SMILES
N/A
Molecular Formula
N/A
Protein Details
β-Glucosidases and β-mannosidases hydrolyze substrates that differ only in the epimer of the nonreducing terminal sugar moiety, but most such enzymes show a strong preference for one activity or the other
Ligand Details
Os7BGlu26 hydrolyzes mannosides via the B2,5 transition state (TS) conformation preferred for mannosides and glucosides via their preferred 4H3/4E TS conformation
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